Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327981 | 0.85 | CYP2C19 (0.52) | EPHX1ALDH1A1CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL31354947 | 0.85 | CYP2C19 (0.52) | EPHX1ALDH1A1CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL14917860 | 0.81 | EPHX1 (0.53) | EPHX1ALDH1A1TDP1CYP2C19CYP1A2 | |
| SCHEMBL6202553 | 0.80 | LMNA (0.50) | ALDH1A1TDP1CYP2C19SMN1; SMN2NPSR1 | |
| SCHEMBL14917721 | 0.80 | EPHX1 (0.51) | EPHX1ALDH1A1TDP1CYP2C19CYP1A2 | |
| SCHEMBL14917822 | 0.78 | EPHX1 (0.50) | EPHX1ALDH1A1TDP1CYP2C19CYP1A2 | |
| SCHEMBL5643025 | 0.77 | KMT2A (0.53) | ALDH1A1TDP1CTSSCTSKLMNA | |
| SCHEMBL23977 | 0.76 | EPHX1 (0.66) | EPHX1CYP2C19CYP1A2CYP2D6PKM | |
| SCHEMBL16881947 | 0.76 | EPHX1 (0.66) | EPHX1CYP2C19CYP1A2CYP2D6PKM | |
| SCHEMBL6359024 | 0.76 | EPHX1 (0.66) | EPHX1CYP2C19CYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3434330-A1 | A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND | Symrise AG (DE) | 2019-01-30 | — | — | EP | claimed |
| US-20120134947-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING COOLING SENSATION EFFECTS AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | claimed |
| US-20120135057-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING A DISPERSED COOLING SENSATION AGENT AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | claimed |
| US-20250367143-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARM INC (US) | 2025-12-04 | — | — | US | disclosed |
| EP-3434330-A1 | A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND | Symrise AG (DE) | 2019-01-30 | — | — | EP | disclosed |
| US-20120135057-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING A DISPERSED COOLING SENSATION AGENT AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120134947-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING COOLING SENSATION EFFECTS AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367143-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR84, GPR68 | EPHX1 4009/4885ALDH1A1 2684/4885TDP1 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.