Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513785 | 1.00 | FPR2 (0.70) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL5926493 | 0.93 | PTPN1 (0.62) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL3991795 | 0.93 | PTPN1 (0.62) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL17696754 | 0.89 | HPGDS (0.65) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL20484576 | 0.88 | PTPN1 (0.55) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL16452951 | 0.88 | CA2 (0.66) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL18620661 | 0.88 | PTPN1 (0.55) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL29619805 | 0.87 | FPR2 (0.58) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL29619797 | 0.87 | FPR2 (0.58) | FPR2PTPN1CA2CA1CTSL | |
| SCHEMBL16452954 | 0.87 | FPR2 (0.58) | FPR2PTPN1CA2CA1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS INC (US) | 2019-05-09 | — | — | US | claimed |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS, INC. | 2012-05-31 | — | — | US | claimed |
| US-20240067950-A1 | MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A | DSM Austria GmbH (AT) | 2024-02-29 | — | — | US | disclosed |
| EP-4263826-A2 | MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A | DSM Austria GmbH (AT) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129517-A2 | MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A | ERBER AKTIENGESELLSCHAFT (AT) | 2022-06-23 | — | — | WO | disclosed |
| CN-114645037-A | Means and methods for detoxification of ochratoxin A | 艾尔柏股份公司 | 2022-06-21 | — | — | CN | disclosed |
| US-10947231-B2 | Processes for the preparation of substituted tetrahydro beta-carbolines | PTC THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS INC (US) | 2019-05-09 | — | — | US | disclosed |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | PTC THERAPEUTICS, INC. | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947231-B2 | Processes for the preparation of substituted tetrahydro beta-carbolines | TPH1, TPH2, HTR1B | FPR2 3980/4885PTPN1 4806/4885CA2 2089/4885 |
| US-20120136154-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | FPR2 3990/4885PTPN1 4806/4885CA2 2162/4885 |
| US-20190135810-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED TETRAHYDRO BETA-CARBOLINES | TPH1, TPH2, HTR1B | FPR2 3980/4885PTPN1 4806/4885CA2 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.