Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 10/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8512624 | 0.93 | ALOX5 (0.50) | ALOX5ALOX15PTGES | |
| SCHEMBL8512623 | 0.88 | NPC1 (0.47) | ALOX5PTGES | |
| SCHEMBL8535303 | 0.86 | MAT2A (0.55) | — | |
| SCHEMBL8532144 | 0.83 | TUBB4A (0.40) | — | |
| SCHEMBL8512448 | 0.81 | KMT2A (0.50) | ALOX5PTGES | |
| SCHEMBL8532926 | 0.79 | MAT2A (0.51) | — | |
| SCHEMBL8538786 | 0.77 | MAT2A (0.45) | ALOX15PTGES | |
| SCHEMBL8537070 | 0.77 | MAT2A (0.57) | — | |
| SCHEMBL20983232 | 0.77 | MAT2A (0.55) | ALOX5 | |
| SCHEMBL8533461 | 0.75 | MAT2A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |