Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 7/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 6/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612709 | 0.90 | KMT2A (0.47) | HRH4RARARARBKMT2AHRH3 | |
| SCHEMBL8514715 | 0.81 | RARA (0.46) | RARARARBKMT2ARARGRXRA | |
| Trifluoroacetic Acid SCHEMBL2223859 | 0.80 | RAB9A (0.47) | RARARARBRARGRXRA | |
| Trifluoroacetic Acid SCHEMBL8514827 | 0.78 | HTR7 (0.51) | RARARARBRARGRXRA | |
| SCHEMBL8512735 | 0.77 | GPR119 (0.48) | RARARARBKMT2A | |
| Trifluoroacetic Acid SCHEMBL8511757 | 0.76 | RARB (0.40) | HRH4RARARARBHRH3RARG | |
| SCHEMBL8511699 | 0.75 | IRAK4 (0.41) | KMT2APRKD1PRKD2PRKD3 | |
| SCHEMBL2014630 | 0.73 | RARA (0.51) | RARARARB | |
| SCHEMBL8514909 | 0.73 | CYP1A2 (0.52) | HRH4RARARARB | |
| Hydrochloric Acid SCHEMBL8512697 | 0.72 | CYP1A2 (0.51) | HRH4RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |