Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514988 | 1.00 | KMO (0.39) | KMOTBK1ACHEAAK1KDM4E | |
| SCHEMBL8515547 | 0.85 | ACHE (0.47) | KMOTBK1ACHEFAAHCHRNA7 | |
| SCHEMBL8514120 | 0.78 | KMO (0.40) | KMOKDM4EALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL8511092 | 0.77 | KMO (0.40) | KMOKDM4EALDH1A1LMNAGAA | |
| SCHEMBL8510840 | 0.76 | KMO (0.43) | KMOKDM4EALDH1A1HPGD | |
| SCHEMBL8515329 | 0.76 | ACHE (0.41) | KMOACHEALDH1A1HPGD | |
| SCHEMBL8510671 | 0.76 | DKK1 (0.44) | KMO | |
| SCHEMBL8514539 | 0.76 | KMO (0.45) | KMOKDM4EALDH1A1LMNAGAA | |
| SCHEMBL8515223 | 0.75 | ACHE (0.38) | TBK1ACHECA9FAAHHCAR2 | |
| SCHEMBL8515226 | 0.75 | ACHE (0.38) | TBK1ACHECA9FAAHHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069852-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF SPHINGOSINE KINASE | ALMAC DISCOVERY LIMITED (GB) | 2012-05-31 | — | — | WO | disclosed |