SCHEMBL8515622

SCHEMBL8515622

C=CCN(O)C(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.33
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7486136 0.85 GRIK1 (0.34) DPP4GRIK1GRIK2ALDH1A1
SCHEMBL251436 0.76 DPP4 (0.36) DPP4GRIK1GRIK2
SCHEMBL170266 0.75
SCHEMBL8728289 0.70 GLO1 (0.32) DPP4
SCHEMBL28876474 0.68 ALDH1A1 (0.34) DPP4ALDH1A1
SCHEMBL7590954 0.68 ALDH1A1 (0.39) DPP4ALDH1A1
SCHEMBL8515616 0.68 ALDH1A1 (0.31) ALDH1A1
SCHEMBL10556450 0.67 ALOX15 (0.33) DPP4GRIK1GRIK2
SCHEMBL757318 0.67 GRIK1 (0.31) GRIK1GRIK2ALDH1A1
SCHEMBL11413701 0.67 ALDH1A1 (0.38) DPP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929198-A HIGH MOLECULAR WEIGHT POLYMERS MODIFIED WITH N-DERIVATIZED COMPOUNDS NALCO CHEMICAL COMPANY (US) 1999-07-27 US claimed
EP-0832851-A1 Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same Nalco Chemical Company (US) 1998-04-01 EP claimed
EP-0832851-A1 Biodegradable poly (amino acids), derivatized amino acid polymers and methods for making the same Nalco Chemical Company (US) 1998-04-01 EP disclosed