Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515616 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11499006 | 0.85 | TDP1 (0.34) | ALDH1A1 | |
| SCHEMBL1843778 | 0.82 | BLM (0.41) | ALDH1A1 | |
| SCHEMBL759009 | 0.82 | BLM (0.41) | ALDH1A1 | |
| SCHEMBL8515620 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2358767 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2358765 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27670709 | 0.75 | ECE1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL5596062 | 0.75 | ECE1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL10355086 | 0.74 | SLC6A2 (0.41) | GRIK1GRIK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099808-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2015-04-09 | — | — | US | claimed |
| US-20110182813-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2011-07-28 | — | — | US | claimed |
| EP-2195366-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | Nirvana's Tree House B.v. (NL) | 2010-06-16 | — | — | EP | claimed |
| WO-2009037313-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | NIRVANA'S TREE HOUSE B.V. (NL) | 2009-03-26 | — | — | WO | claimed |
| US-20240116895-A1 | ESTER SUBSTITUTED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240100032-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | disclosed |
| EP-3485881-B1 | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS | HARVARD COLLEGE (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20240076305-A1 | Phosphonium Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2024-03-07 | — | — | US | disclosed |
| US-11701370-B2 | Phosphonium ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11696912-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2023-06-22 | — | — | US | disclosed |
| CN-113430664-B | Fibers comprising microfibrillated cellulose and methods of making fibers and nonwoven materials therefrom | 菲博林科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-0676953-A1 | PLASTICIZED BIOERODIBLE CONTROLLED DELIVERY SYSTEM | INSITE VISION INCORPORATED (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0676952-A1 | BIOERODIBLE CONTROLLED DELIVERY SYSTEM | INSITE VISION INCORPORATED (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014416-A1 | BIOERODIBLE CONTROLLED DELIVERY SYSTEM | INSITE VISION INCORPORATED (US) | 1994-07-07 | — | — | WO | disclosed |
| WO-1994014417-A1 | PLASTICIZED BIOERODIBLE CONTROLLED DELIVERY SYSTEM | INSITE VISION INCORPORATED (US) | 1994-07-07 | — | — | WO | disclosed |
| US-5160745-A | Three dimensional network, sustained release of hormones, peptides, vaccines, enzymes | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1992-11-03 | — | — | US | disclosed |
| EP-0467389-A2 | Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1992-01-22 | — | — | EP | disclosed |
| US-4741872-A | Preparation of biodegradable microspheres useful as carriers for macromolecules | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0245820-A2 | Biodegradable microspheres as a carrier for macromolecules | The University of Kentucky Research Foundation (US) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182813-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | GLUL, ASNS, ARGLU1 | GRIK1 71/4885GRIK2 66/4885ALDH1A1 2720/4885 |
| US-20150099808-A1 | AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS | GLUL, ASNS, ARGLU1 | GRIK1 71/4885GRIK2 66/4885ALDH1A1 2720/4885 |
| US-20240100032-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, ASIC1, TRPA1 | GRIK1 233/4885GRIK2 266/4885ALDH1A1 2571/4885 |
| US-20240116895-A1 | ESTER SUBSTITUTED ION CHANNEL BLOCKERS AND METHODS FOR USE | TRPV1, TRPA1, TRPV2 | GRIK1 194/4885GRIK2 212/4885ALDH1A1 1138/4885 |
| US-11696912-B2 | Charged ion channel blockers and methods for use | TRPV1, ASIC1, TRPA1 | GRIK1 233/4885GRIK2 266/4885ALDH1A1 2571/4885 |
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV2, TRPV5 | GRIK1 205/4885GRIK2 215/4885ALDH1A1 2736/4885 |
| US-11701370-B2 | Phosphonium ion channel blockers and methods for use | TRPV1, TRPV5, TRPA1 | GRIK1 192/4885GRIK2 219/4885ALDH1A1 3411/4885 |
| US-20240076305-A1 | Phosphonium Ion Channel Blockers and Methods for Use | TRPV1, TRPV5, TRPA1 | GRIK1 192/4885GRIK2 219/4885ALDH1A1 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.