Water

Water

SCHEMBL8515735

O.O.O.O.O.[Cl-].[Cl-].[Mg+2]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28154778 1.00
Water SCHEMBL28617541 1.00
Water SCHEMBL27139545 1.00
Water SCHEMBL28572506 1.00
Water SCHEMBL2178451 1.00
Water SCHEMBL50183 1.00
Water SCHEMBL1051679 1.00
Water SCHEMBL11417389 1.00
Water SCHEMBL139170 1.00
Water SCHEMBL27991690 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028435-B High-density tundish dry material and preparation method thereof 张家港市恒乐阳方高温材料有限公司 2023-10-20 CN claimed
CN-115028435-A High-density tundish dry material and preparation method thereof 张家港市恒乐阳方高温材料有限公司 2022-09-09 CN claimed
CN-113463159-B Preparation method of high-wear-resistance rose petal effect titanium alloy surface 西安理工大学 2022-07-22 CN claimed
CN-113463159-A Preparation method of high-wear-resistance rose petal effect titanium alloy surface 西安理工大学 2021-10-01 CN claimed
CN-221645783-U Spiral pile foundation based on urease bacterial reinforcement technology 中国电建集团华东勘测设计研究院有限公司 2024-09-03 CN disclosed
CN-118490729-A 5 Alpha-reductase inhibitor and application thereof in hair-growth preventing products 扬州博研生物技术服务有限公司 2024-08-16 CN disclosed
CN-117084977-A Pilocarpine hydrochloride eye drops and preparation method thereof 广州市力鑫药业有限公司 2023-11-21 CN disclosed
CN-115028435-B High-density tundish dry material and preparation method thereof 张家港市恒乐阳方高温材料有限公司 2023-10-20 CN disclosed
CN-115028435-A High-density tundish dry material and preparation method thereof 张家港市恒乐阳方高温材料有限公司 2022-09-09 CN disclosed
CN-113463159-B Preparation method of high-wear-resistance rose petal effect titanium alloy surface 西安理工大学 2022-07-22 CN disclosed
CN-108434126-B Dry powder formulations and methods for treating pulmonary diseases 普马特里克斯营业公司 2021-11-19 CN disclosed
CN-113463159-A Preparation method of high-wear-resistance rose petal effect titanium alloy surface 西安理工大学 2021-10-01 CN disclosed
CN-113388388-A Rare earth halogen silicate fluorescent powder and preparation method and application thereof 厦门大学 2021-09-14 CN disclosed
US-20180284123-A1 BARCODED RAPID ASSAY PLATFORM USEFUL FOR EFFICIENT ANALYSIS OF CANDIDATE MOLECULES AND METHODS OF MAKING AND USING THE PLATFORM CALIFORNIA INSTITUTE OF TECHNOLOGY 2018-10-04 US disclosed
WO-2018183969-A1 BARCODED RAPID ASSAY PLATFORM FOR EFFICIENT ANALYSIS OF CANDIDATE MOLECULES AND METHODS OF MAKING AND USING THE PLATFORM CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-10-04 WO disclosed
US-20140037574-A1 PHARMACEUTICAL COMPOSITION UNIVERSITY OF THE WITWATERSRAND (ZA) 2014-02-06 US disclosed
WO-2012070030-A1 A PHARMACEUTICAL COMPOSITION UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) 2012-05-31 WO disclosed