SCHEMBL8515902

SCHEMBL8515902

Fc1c(F)c(F)c(Oc2ccc(Sc3ccc(Oc4c(F)c(F)c(F)c(F)c4F)cc3)cc2)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
MAPT P10636 4/20 0.38
POLB P06746 1/20 0.38
HSP90AA1 P07900 1/20 0.38
STS P08842 1/20 0.38
HTT P42858 2/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
NR1H2 P55055 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18879511 0.78 ACHE (0.37) HSD17B10MAPTPOLBHTTHPGD
SCHEMBL18879532 0.75 MAPT (0.35) HSD17B10MAPTHTTHPGDMEN1
SCHEMBL24413619 0.74 ESR1 (0.59) HSD17B10CA12CA1CA2CA7
SCHEMBL5546635 0.74 HSD17B10 (0.47) HSD17B10CA12CA1CA2CA7
SCHEMBL27092113 0.73 CA12 (0.62) HSD17B10CA12CA1CA2CA7
SCHEMBL1656495 0.71 ALDH1A1 (0.62) HSD17B10CA12CA1CA2CA7
SCHEMBL5330786 0.71 ESR1 (0.62) HSD17B10CA12CA1CA2CA7
SCHEMBL14189682 0.70 HSD17B10 (0.35) HSD17B10MAPTHTTHPGDMEN1
SCHEMBL2188181 0.70 HSD17B10 (0.43) HSD17B10CA12CA1CA2CA7
SCHEMBL14424439 0.70 HSD17B10 (0.43) HSD17B10CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932797-B2 Photoacid generators DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-20120141939-A1 PHOTOACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2012-06-07 US disclosed
EP-2458440-A1 Photoacid generators Rohm and Haas Electronic Materials LLC (US) 2012-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120141939-A1 PHOTOACID GENERATORS F10, GNG2, H1-0 HSD17B10 2645/4885CA12 580/4885CA1 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.