Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 5/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516587 | 0.89 | F2RL3 (0.42) | TP53POLB | |
| SCHEMBL8516330 | 0.89 | TP53 (0.42) | TP53RXFP1POLBEDNRBEDNRA | |
| SCHEMBL8516993 | 0.87 | CAMK2D (0.37) | TP53RXFP1EDNRBMAPT | |
| SCHEMBL7663837 | 0.87 | TP53 (0.44) | TP53RXFP1POLBEDNRBEDNRA | |
| SCHEMBL7663857 | 0.84 | RXFP1 (0.40) | TP53RXFP1POLBMAPTSMN1; SMN2 | |
| SCHEMBL8516339 | 0.84 | F2RL3 (0.44) | TP53POLBMAPT | |
| SCHEMBL7660574 | 0.83 | TP53 (0.39) | TP53RXFP1POLBMAPTSMN1; SMN2 | |
| SCHEMBL7655899 | 0.83 | TP53 (0.39) | TP53RXFP1POLBMAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL8516406 | 0.82 | TP53 (0.42) | TP53RXFP1POLBEDNRBEDNRA | |
| SCHEMBL8516249 | 0.77 | F2RL3 (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |