Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 9/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516587 | 0.94 | F2RL3 (0.42) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516793 | 0.87 | CAMK2D (0.48) | CNR2 | |
| SCHEMBL8516977 | 0.86 | CAMK2D (0.46) | CNR2 | |
| SCHEMBL8516409 | 0.84 | TP53 (0.43) | POLBTP53MAPT | |
| SCHEMBL7654522 | 0.83 | ALDH1A1 (0.42) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7851651 | 0.81 | PDE4A (0.38) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7659856 | 0.81 | PDE4A (0.38) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8516249 | 0.81 | F2RL3 (0.40) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7663917 | 0.81 | PDE4A (0.38) | F2RL3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7664799 | 0.80 | PDE4A (0.37) | F2RL3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |