Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663691 | 0.85 | ASH1L (0.38) | ASH1LTDP1CAMK2DGSK3BQPCT | |
| SCHEMBL8366761 | 0.84 | ASH1L (0.37) | ASH1LTDP1 | |
| SCHEMBL8516619 | 0.84 | ASH1L (0.43) | ASH1LTDP1CAMK2DGSK3BQPCT | |
| SCHEMBL8367882 | 0.83 | RAB9A (0.44) | ASH1LTDP1CAMK2DGSK3BQPCT | |
| SCHEMBL7659523 | 0.82 | ASH1L (0.35) | ASH1LTDP1 | |
| SCHEMBL7654550 | 0.82 | KMT2A (0.36) | ASH1LTDP1 | |
| SCHEMBL8366774 | 0.81 | ASH1L (0.34) | ASH1LTDP1 | |
| Acetic Acid SCHEMBL8516995 | 0.81 | ALDH1A1 (0.38) | ASH1LTDP1CAMK2DIDO1GSK3B | |
| SCHEMBL8516682 | 0.79 | GSK3B (0.38) | CAMK2DGSK3B | |
| Acetic Acid SCHEMBL7815363 | 0.78 | CFTR (0.45) | ASH1LTDP1CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |