Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363292 | 0.97 | KDM4E (0.35) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9048962 | 0.79 | PDCD1 (0.34) | KDM4EALDH1A1HPGD | |
| SCHEMBL8146941 | 0.78 | GRIN1 (0.39) | KDM4EHSD17B10HPGD | |
| SCHEMBL8154329 | 0.76 | KMT2A (0.31) | KDM4EALDH1A1 | |
| SCHEMBL8147658 | 0.75 | PDCD1 (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL8150807 | 0.75 | NPC1 (0.41) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL8148345 | 0.74 | ALDH1A1 (0.48) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL8149445 | 0.74 | TERT (0.36) | KDM4E | |
| SCHEMBL8365424 | 0.71 | — | — | |
| SCHEMBL8536552 | 0.67 | GAA (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045926-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-09-16 | — | — | WO | disclosed |