Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339407 | 0.88 | HDAC3 (0.43) | HDAC3HDAC1KDM4EKMT2ACA2 | |
| SCHEMBL8516959 | 0.86 | HDAC3 (0.51) | HDAC3HDAC1KDM4EKMT2ACA2 | |
| SCHEMBL15044687 | 0.82 | MMP13 (0.57) | KMT2APOLBSMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL8516912 | 0.80 | LMNA (0.50) | HDAC3HDAC1KDM4EKMT2ACA2 | |
| SCHEMBL9316666 | 0.80 | HDAC3 (0.43) | HDAC3HDAC1KDM4EKMT2ACA2 | |
| SCHEMBL10294734 | 0.79 | KDM4E (0.57) | HDAC3HDAC1KDM4EKMT2APOLB | |
| SCHEMBL10261106 | 0.77 | CA12 (0.49) | HDAC3HDAC1KMT2ACA12CA9 | |
| SCHEMBL10077477 | 0.76 | NFKB1 (0.60) | HDAC3HDAC1KDM4EKMT2APOLB | |
| SCHEMBL27413017 | 0.76 | LMNA (0.47) | KDM4ECA2CA12CA9ALDH1A1 | |
| SCHEMBL9316670 | 0.74 | CA2 (0.37) | CA2CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586331-B1 | Process for dyeing synthetic polyamid fibre materials | CIBA GEIGY AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| US-5356440-A | Fiber-reactive dyes containing only one sulfo group | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0586331-A2 | Process for dyeing synthetic polyamid fibre materials | CIBA-GEIGY AG (CH) | 1994-03-09 | — | — | EP | disclosed |