Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921922 | 0.73 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| SCHEMBL1551949 | 0.65 | CYP3A4 (0.57) | ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL1963148 | 0.64 | HPGD (0.42) | ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL17242666 | 0.63 | TSHR (0.45) | ALDH1A1MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL5587187 | 0.63 | HPGD (0.41) | ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL3839311 | 0.62 | CYP3A4 (0.56) | ALDH1A1MAPTPOLB | |
| SCHEMBL3843245 | 0.62 | TSHR (0.56) | ALDH1A1MAPTTDP1POLB | |
| SCHEMBL27321459 | 0.62 | TSHR (0.55) | ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL5691196 | 0.62 | GPR35 (0.45) | ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL30425872 | 0.62 | GPR35 (0.45) | ALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907362-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0907362-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049399-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |