Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617693 | 0.83 | ALDH1A1 (0.43) | MAOBMAPTRAB9ANPC1SMN1; SMN2 | |
| Benzene SCHEMBL9420957 | 0.80 | TSHR (0.41) | CA12CA1CA2CA6CA9 | |
| SCHEMBL69866 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL69865 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL31045928 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL6512127 | 0.78 | CA12 (0.54) | MAOBCA12CA1CA2CA6 | |
| SCHEMBL9676480 | 0.78 | CA12 (0.54) | MAOBCA12CA1CA2CA6 | |
| Hydrazine SCHEMBL27911717 | 0.76 | LOXL2 (0.50) | CA12CA1CA2CA9MAPT | |
| SCHEMBL3782123 | 0.76 | CA12 (0.52) | MAOBCA12CA1CA2CA6 | |
| SCHEMBL14437429 | 0.76 | TRPA1 (0.67) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |