Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518354 | 0.83 | MAOB (0.49) | ALDH1A1MAOBMAPTRAB9ANPC1 | |
| SCHEMBL10478230 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTRAB9ANPC1 | |
| SCHEMBL13283358 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRMAOBMAPTRAB9A | |
| Hydrazine SCHEMBL27911717 | 0.75 | LOXL2 (0.50) | ALDH1A1TSHRMAPTRAB9ANPC1 | |
| SCHEMBL27510 | 0.75 | ALDH1A1 (0.59) | ALDH1A1TSHRL3MBTL1PARP1ATM | |
| Methane SCHEMBL9490009 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11596733 | 0.74 | TRPA1 (0.50) | ALDH1A1TSHRMAPTRAB9ANPC1 | |
| SCHEMBL3019453 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRMAOBMAPTRAB9A | |
| SCHEMBL413744 | 0.74 | TDP1 (0.44) | ALDH1A1TSHRMAPTRAB9ANPC1 | |
| SCHEMBL14670993 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863860-B | N-substituted phenyl-3-sulfonyl aminobenzamide compound, preparation thereof and application thereof in resisting breast cancer activity | 温州医科大学 | 2021-08-06 | — | — | CN | disclosed |