O-Xylene

O-Xylene

SCHEMBL8518692

Cc1ccccc1C.ClC(Cl)(Cl)Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
ACHE P22303 3/20 0.71
ALDH1A1 P00352 4/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 2/20 0.42
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
ESR1 P03372 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL6933035 0.93 TSHR (0.83) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL9152232 0.90 TSHR (0.67) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL28646369 0.86 TSHR (0.71) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11035539 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10522915 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL2854068 0.84
O-Xylene SCHEMBL8216257 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11034038 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL772 0.84
O-Xylene SCHEMBL170581 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111948096-A Method for detecting components of coated fabric 宁波升一检测技术服务有限公司 2020-11-17 CN claimed
US-20240115471-A1 NON-STICKY SMOOTH STABLE COMPOSITION L'OREAL (FR) 2024-04-11 US disclosed
EP-4259087-A1 NON-STICKY SMOOTH STABLE COMPOSITION L'OREAL (FR) 2023-10-18 EP disclosed
WO-2023113004-A1 NON-STICKY SMOOTH STABLE COMPOSITION L'OREAL (FR) 2023-06-22 WO disclosed
US-20230070691-A1 STABLE COMPOSITION COMPRISING COMBINATION OF SPECIFIC INGREDIENTS L'OREAL (FR) 2023-03-09 US disclosed
CN-114786645-A Stable compositions comprising a combination of specific ingredients 莱雅公司 2022-07-22 CN disclosed
WO-2022124387-A1 NON-STICKY SMOOTH STABLE COMPOSITION L'OREAL (FR) 2022-06-16 WO disclosed
WO-2021125118-A1 STABLE COMPOSITION COMPRISING COMBINATION OF SPECIFIC INGREDIENTS L'OREAL (FR) 2021-06-24 WO disclosed
CN-111948096-A Method for detecting components of coated fabric 宁波升一检测技术服务有限公司 2020-11-17 CN disclosed
CN-104678706-B Colored curable resin composition 东友精细化工有限公司 2019-11-29 CN disclosed
CN-1302163-C High strength polyethylene-2, 6-naphthalate fibers HYOSUNG CORP (KR) 2007-02-28 CN disclosed
CN-1273658-C High tenacity polyethylene-2,6-naphthalate fibers having excellent processability HYOSUNG CORP (KR) 2006-09-06 CN disclosed
CN-1255584-C Polyester compound filament HYOSONG CO LTD (KR) 2006-05-10 CN disclosed
CN-1681980-A High strength polyethylene-2, 6-naphthalate fibers HYOSUNG CORP (KR) 2005-10-12 CN disclosed
CN-1195110-C High Strength polynaphthalic acid subethyl ester fiber HYOSOONG CO LTD (KR) 2005-03-30 CN disclosed
CN-1576404-A High tenacity polyethylene-2,6-naphthalate fibers having excellent processability HYOSUNG CORP (KR) 2005-02-09 CN disclosed
CN-1397669-A High strength polynaphthalic acid subethyl ester fiber HYOSOONG CO LTD (KR) 2003-02-19 CN disclosed
CN-1385562-A Polyester compound filament HYOSONG CO LTD (KR) 2002-12-18 CN disclosed
US-5897347-A HEATING SILICON FILM AND CRYSTALLIZATION CATALYST; ANNEALING FILM TO REMOVE CATALYST SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 1999-04-27 US disclosed
EP-0025200-A1 Process for preparing polyphenylene oxide graft copolymers KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115471-A1 NON-STICKY SMOOTH STABLE COMPOSITION FFAR3, FFAR2, ELOVL3 TSHR 1922/4885ACHE 3705/4885ALDH1A1 3174/4885
US-20230070691-A1 STABLE COMPOSITION COMPRISING COMBINATION OF SPECIFIC INGREDIENTS LTB4R, LTB4R2, HACD3 TSHR 4043/4885ACHE 2020/4885ALDH1A1 4445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.