Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 2/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564026 | 0.84 | SLC6A4 (0.44) | LTA4HTSHRSLC6A4CA4ADRA2A | |
| SCHEMBL982079 | 0.78 | LTA4H (0.52) | LTA4HSLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL8717190 | 0.78 | LMNA (0.42) | TSHRSLC6A4CA4 | |
| SCHEMBL2035765 | 0.76 | CA4 (0.44) | LTA4HTSHRSLC6A4CA4ADRA2A | |
| SCHEMBL2031146 | 0.75 | SLC6A4 (0.41) | LTA4HTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16382776 | 0.72 | NPSR1 (0.47) | TSHRSLC6A4 | |
| SCHEMBL18297906 | 0.71 | SLC6A4 (0.39) | LTA4HTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10942730 | 0.71 | SLC6A4 (0.39) | LTA4HTSHRSLC6A4CA4ADRA2A | |
| SCHEMBL8518703 | 0.71 | SLC6A4 (0.39) | LTA4HTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16348652 | 0.70 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3ADRA2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |