Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520343 | 0.83 | CASP1 (0.65) | CASP1 | |
| SCHEMBL5679090 | 0.81 | CASP1 (1.00) | CASP1 | |
| SCHEMBL8519014 | 0.80 | CASP1 (0.75) | CASP1 | |
| SCHEMBL5683116 | 0.75 | CASP1 (0.59) | CASP1 | |
| SCHEMBL5678964 | 0.74 | CASP1 (0.86) | CASP1 | |
| SCHEMBL6279917 | 0.73 | SLC1A3 (0.50) | CASP1 | |
| SCHEMBL7744231 | 0.73 | CASP1 (0.51) | CASP1 | |
| SCHEMBL5680753 | 0.69 | CASP1 (0.63) | CASP1 | |
| SCHEMBL5683297 | 0.67 | CASP1 (0.78) | CASP1 | |
| SCHEMBL12994829 | 0.67 | CASP1 (0.60) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1$g(b) CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016504-A2 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |