Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 10/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849395 | 0.79 | CASP1 (0.57) | CASP1MMP2MMP13MMP14ADRA2C | |
| SCHEMBL8520343 | 0.77 | CASP1 (0.65) | CASP1L3MBTL1ICMT | |
| SCHEMBL7080300 | 0.76 | ALDH1A1 (0.48) | MTNR1B | |
| SCHEMBL29165186 | 0.75 | CA9 (0.55) | — | |
| SCHEMBL7953769 | 0.75 | CASP1 (0.55) | CASP1L3MBTL1POLB | |
| SCHEMBL2810873 | 0.75 | EPHX2 (0.55) | — | |
| SCHEMBL20998613 | 0.75 | CASP1 (0.58) | CASP1ADAMTS4MMP1MMP2MMP13 | |
| SCHEMBL7080256 | 0.74 | HSD17B10 (0.50) | L3MBTL1POLBATMMTNR1BNPSR1 | |
| SCHEMBL7076725 | 0.74 | MTNR1B (0.48) | MTNR1BNPSR1 | |
| SCHEMBL2640221 | 0.74 | MEN1 (0.58) | L3MBTL1POLBATMMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |