Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518404 | 0.92 | PTGS2 (0.36) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL8518395 | 0.92 | KIF11 (0.36) | HSD11B1CA2KIF11MEN1KMT2A | |
| SCHEMBL8519802 | 0.91 | HSD11B1 (0.37) | POLBHSD11B1KIF11NPC1 | |
| SCHEMBL8519027 | 0.90 | PTGS2 (0.33) | PTGS2PTGS1GRM5POLBGAA | |
| SCHEMBL8518495 | 0.90 | PPARA (0.34) | PTGS2HSD11B1KIF11HTTKMT2A | |
| SCHEMBL8518483 | 0.88 | NR3C1 (0.36) | PTGS2KDM4EMEN1HTTKMT2A | |
| SCHEMBL8519158 | 0.88 | STS (0.39) | PTGS2PTGS1HSD11B1CA2KIF11 | |
| SCHEMBL8519562 | 0.84 | UCHL1 (0.35) | PTGS2RXFP1CA9MEN1KMT2A | |
| SCHEMBL8519024 | 0.83 | HSD11B1 (0.40) | GAAHSD11B1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8518628 | 0.82 | TDP1 (0.37) | KMT2ANR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |