Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407573 | 0.89 | NR1H4 (0.50) | RAB9APLAUKCNH2SCN10AMEN1 | |
| SCHEMBL8410251 | 0.86 | LMNA (0.56) | RAB9AKCNH2SCN10AMEN1KMT2A | |
| SCHEMBL9238331 | 0.83 | MLYCD (0.53) | RAB9AMEN1NPC1KMT2ANR1H4 | |
| Hydrochloric Acid SCHEMBL8718113 | 0.83 | ITGB3 (0.70) | ITGB3ITGA2BPLAUBRD4TRPV1 | |
| Hydrochloric Acid SCHEMBL9236526 | 0.79 | ITGB3 (0.55) | RAB9AITGB3ITGA2BMEN1NPC1 | |
| SCHEMBL3628694 | 0.78 | CYP11B1 (0.56) | MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL7395422 | 0.77 | BRD4 (0.43) | RAB9AKCNH2SCN10AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3628690 | 0.77 | CYP11B1 (0.55) | MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL3926844 | 0.77 | FFAR1 (0.54) | RAB9ACYP11B1CYP11B2SIRT2 | |
| SCHEMBL9253364 | 0.76 | CYP11B1 (0.52) | RAB9AMEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |