Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898515 | 0.93 | ALDH1A1 (0.35) | ALDH1A1KDM4EALOX15LMNATSHR | |
| SCHEMBL8401272 | 0.89 | ITGB3 (0.39) | ALDH1A1KDM4ETSHRSMN1; SMN2ITGB3 | |
| SCHEMBL8519494 | 0.75 | ITGB3 (0.39) | ALDH1A1KDM4ELMNAHPGDITGB3 | |
| SCHEMBL8898192 | 0.75 | CCKBR (0.38) | ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL8401264 | 0.74 | CACNA1G (0.42) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL8401279 | 0.69 | CACNA1G (0.41) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL8402359 | 0.65 | KDM4E (0.36) | ALDH1A1KDM4ELMNAHPGDATM | |
| SCHEMBL8398832 | 0.65 | ITGB3 (0.40) | ALDH1A1KDM4ETSHRSMN1; SMN2ITGB3 | |
| SCHEMBL7442287 | 0.62 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7338319 | 0.61 | PARP1 (0.44) | ALDH1A1TSHRSMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |