Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401279 | 0.92 | CACNA1G (0.41) | CACNA1GCACNA1HCACNA1IALDH1A1PARK7 | |
| SCHEMBL8399373 | 0.75 | ITGB3 (0.40) | CACNA1GCACNA1HCACNA1IITGB3ITGAV | |
| SCHEMBL8519715 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MDM2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8898515 | 0.69 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KDM4ELMNATSHR | |
| SCHEMBL8195620 | 0.68 | ITGB3 (0.49) | CACNA1GCACNA1HCACNA1ISMN1; SMN2ITGB3 | |
| SCHEMBL21997414 | 0.61 | CA1 (0.67) | ALDH1A1PARK7ALDH2ALDH3A1SMN1; SMN2 | |
| SCHEMBL28326301 | 0.59 | L3MBTL1 (0.58) | CACNA1GCACNA1HCACNA1IALDH1A1PARK7 | |
| SCHEMBL24796467 | 0.59 | HDAC6 (0.55) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL7416500 | 0.58 | CACNA1G (0.41) | CACNA1GCACNA1HCACNA1IALDH1A1PARK7 | |
| Benzylamine SCHEMBL3188490 | 0.58 | LOXL2 (0.74) | SMN1; SMN2TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |