Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002508 | 0.69 | DPP4 (0.50) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL20472978 | 0.69 | DPP4 (0.50) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL14615324 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL18023413 | 0.68 | PTGS1 (0.36) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL5368752 | 0.65 | ALDH1A1 (0.35) | — | |
| SCHEMBL8519727 | 0.64 | ARG1 (0.33) | — | |
| SCHEMBL24572029 | 0.63 | ACLY (0.34) | — | |
| SCHEMBL14724245 | 0.63 | ALDH1A1 (0.33) | — | |
| SCHEMBL28665729 | 0.63 | PGD (0.32) | — | |
| Hydrochloric Acid SCHEMBL27936404 | 0.62 | ACLY (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |