Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004419 | 0.79 | ARG1 (0.51) | ARG1ARG2 | |
| SCHEMBL1809322 | 0.76 | ARG1 (0.41) | ARG1ARG2MMP8 | |
| SCHEMBL7060314 | 0.66 | — | — | |
| SCHEMBL8519724 | 0.64 | PAX8 (0.32) | — | |
| SCHEMBL9905565 | 0.63 | ARG1 (0.33) | ARG1ARG2 | |
| SCHEMBL5014848 | 0.63 | ARG1 (0.46) | ARG1ARG2 | |
| SCHEMBL25435895 | 0.62 | ARG1 (0.39) | ARG1ARG2 | |
| SCHEMBL1915583 | 0.62 | ARG1 (0.32) | ARG1ARG2 | |
| SCHEMBL1809316 | 0.62 | HDAC8 (0.39) | MMP8 | |
| SCHEMBL10305471 | 0.62 | ARG1 (0.41) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |