Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519249 | 0.85 | MTNR1A (0.37) | MTNR1AELANE | |
| SCHEMBL8519403 | 0.78 | CTRC (0.37) | GABRA1GABRB2 | |
| SCHEMBL52006 | 0.74 | — | — | |
| SCHEMBL8518760 | 0.72 | CYP2A6 (0.35) | — | |
| SCHEMBL12681552 | 0.71 | ALDH1A1 (0.46) | GABRA1GABRB2MAOAPDK2HTT | |
| SCHEMBL2602430 | 0.69 | EED (0.46) | GABRA1GABRB2MTNR1ASMN1; SMN2 | |
| SCHEMBL14145511 | 0.69 | CETP (0.39) | GABRA1GABRB2MAOAPDK2HTT | |
| SCHEMBL2663368 | 0.69 | MPO (0.41) | GABRA1GABRB2MAOA | |
| SCHEMBL23719108 | 0.68 | GABRA1 (0.36) | GABRA1GABRB2MAOAPDK2HTT | |
| SCHEMBL12681609 | 0.68 | PDK2 (0.38) | GABRA1GABRB2MAOAPDK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679662-B1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO LTD (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5728641-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0679662-A1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO. LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |