Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750202 | 0.74 | NOTUM (0.43) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL4632276 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2RAB9AL3MBTL1HPGDKDM4E | |
| SCHEMBL8633273 | 0.67 | L3MBTL1 (0.40) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| Anthraquinone SCHEMBL28110119 | 0.62 | ELANE (0.64) | SMN1; SMN2L3MBTL1HSD17B10ALDH1A1BCHE | |
| SCHEMBL21359114 | 0.62 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL1955620 | 0.61 | BCHE (0.55) | SMN1; SMN2L3MBTL1KDM4EHSD17B10ALDH1A1 | |
| Anthraquinone SCHEMBL28110120 | 0.61 | ELANE (0.55) | SMN1; SMN2NPC1RAB9AL3MBTL1HSD17B10 | |
| SCHEMBL11080358 | 0.61 | CTSK (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL17164501 | 0.60 | CTSK (0.49) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL22638051 | 0.60 | ALDH1A1 (0.43) | RAB9AL3MBTL1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934282-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015535-A1 | 1,4-BENZODIAZEPINONES AND THEIR USES AS CCK ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |