SCHEMBL8520463

SCHEMBL8520463

C=CCN(CC=C)C(=Cc1ccccc1)c1ccc2ccccc2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.49
MAPT P10636 7/20 0.49
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
ALDH1A1 P00352 6/20 0.49
HPGD P15428 1/20 0.49
MGAM O43451 1/20 0.43
SMN1; SMN2 Q16637 7/20 0.41
GAA P10253 4/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CNR2 P34972 1/20 0.40
RAB9A P51151 5/20 0.39
LMNA P02545 4/20 0.39
NPC1 O15118 2/20 0.39
KDM4C Q9H3R0 1/20 0.39
RECQL P46063 1/20 0.39
PKM P14618 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494588 0.83 MEN1 (0.51) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL1348645 0.79 LMNA (0.55) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL9617201 0.77 MAPT (0.54) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL8519976 0.76 RAB9A (0.47) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL4940758 0.76 CYP1A2 (0.45) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL15549323 0.73 MAPT (0.62) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL8822084 0.72 MAPT (0.48) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL27560797 0.70 MAPT (0.59) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL28002084 0.70 MAPT (0.59) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL19591528 0.70 MAPT (0.59) KDM4EMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11171909-A None JP disclosed
JP-11171908-A None JP disclosed
JP-H11171908-A PHOTOPOLYMERIZABLE COMPOSITION AND SHEET FOR RECORDING BROTHER IND LTD 1999-06-29 JP disclosed
JP-H11171909-A PHOTOPOLYMERIZABLE COMPOSITION AND SHEET FOR RECORDING BROTHER IND LTD 1999-06-29 JP disclosed