Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822084 | 0.90 | MAPT (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1348645 | 0.83 | LMNA (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8822056 | 0.81 | ALDH1A1 (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2494588 | 0.79 | MEN1 (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8520463 | 0.77 | KDM4E (0.49) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15549323 | 0.77 | MAPT (0.62) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19591528 | 0.74 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11400893 | 0.72 | MAPT (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9446234 | 0.71 | TRPM8 (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6031703 | 0.71 | TRPM8 (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4018074-A | — | — | None | — | — | JP | disclosed |
| JP-H0418074-A | TRIPHENYLAMINE DERIVATIVE | HITACHI LTD | 1992-01-22 | — | — | JP | disclosed |