Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224728 | 0.89 | KDM4E (0.44) | TSHRKDM4EALDH1A1POLBGAA | |
| SCHEMBL15697704 | 0.87 | KDM4E (0.47) | TSHRKDM4EALDH1A1POLBGAA | |
| SCHEMBL4806320 | 0.80 | LMNA (0.46) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL18177204 | 0.80 | POLB (0.38) | KDM4EALDH1A1POLBGAAMEN1 | |
| SCHEMBL20562200 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1POLBGAAMEN1 | |
| SCHEMBL22932423 | 0.79 | KDM4E (0.47) | TSHRKDM4EALDH1A1POLBGAA | |
| SCHEMBL19069268 | 0.79 | KDM4E (0.42) | TSHRKDM4EALDH1A1POLBGAA | |
| SCHEMBL17553368 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1POLBGAAMEN1 | |
| SCHEMBL20563463 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1POLBGAAMEN1 | |
| SCHEMBL18952849 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1POLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718600-B1 | SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE | EXXONMOBIL RES & ENG CO (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7538251-B2 | Synthesis of severely sterically hindered secondary aminoether alcohols from a ketene and/or carboxylic acid halide and/or carboxylic acid anhydride | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1718600-A4 | SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE | EXXONMOBIL RES & ENG CO (US) | 2008-06-25 | — | — | EP | disclosed |
| US-20070287866-A1 | Synthesis of Severely Sterically Hindered Secondary Aminoether Alcohols from a Ketene and/or Carboxylic Acid Halide and/or Carboxylic Acid Anhydride | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-12-13 | — | — | US | disclosed |
| EP-1718600-A1 | SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE | ExxonMobil Research and Engineering Company (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082836-A1 | SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287866-A1 | Synthesis of Severely Sterically Hindered Secondary Aminoether Alcohols from a Ketene and/or Carboxylic Acid Halide and/or Carboxylic Acid Anhydride | ADH1A, ADH1C, ALDH7A1 | TSHR 1273/4885KDM4E 675/4885ALDH1A1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.