Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.66 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.66 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292457 | 0.83 | PLOD2 (0.65) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL1925385 | 0.79 | PLOD2 (1.00) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL7075878 | 0.79 | PLOD2 (0.69) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL29554726 | 0.79 | PLOD2 (0.89) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL10320930 | 0.79 | PLOD2 (0.89) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL6440012 | 0.77 | PLOD2 (0.67) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Trifluoroacetic Acid SCHEMBL4883046 | 0.77 | PLOD2 (0.63) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| SCHEMBL70367 | 0.77 | CES1 (0.56) | PLOD2PLOD3PLOD1ALDH1A1GAA | |
| SCHEMBL2424897 | 0.76 | LMNA (0.65) | PLOD2PLOD3PLOD1ALDH1A1APP | |
| Niacinamide SCHEMBL5712623 | 0.76 | F7 (0.73) | PLOD2PLOD3PLOD1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925795-A | Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates | ZENECA LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| US-5707930-A | HERBICIDES, AGRICULTURE | ZENECA LIMITED (GB) | 1998-01-13 | — | — | US | disclosed |