Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209607 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4ETSHRTP53 | |
| SCHEMBL8143485 | 0.72 | CLCN2 (0.39) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR | |
| SCHEMBL7843687 | 0.70 | NOTUM (0.50) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR | |
| SCHEMBL8139454 | 0.68 | FABP4 (0.39) | TSHRRARARARBRARGWEE1 | |
| SCHEMBL432644 | 0.67 | TSHR (0.64) | ALDH1A1SMN1; SMN2KDM4ETSHRTP53 | |
| SCHEMBL29886586 | 0.67 | TSHR (0.64) | ALDH1A1SMN1; SMN2KDM4ETSHRTP53 | |
| SCHEMBL11102271 | 0.67 | KDM4E (0.55) | ALDH1A1GAAKDM4ETSHREPHX2 | |
| SCHEMBL107955 | 0.66 | TSHR (0.52) | ALDH1A1SMN1; SMN2KDM4ETSHRNOTUM | |
| SCHEMBL217628 | 0.66 | TSHR (0.61) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR | |
| SCHEMBL32690872 | 0.66 | TSHR (0.61) | ALDH1A1SMN1; SMN2GAAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948917-A | INTERMEDIATE FOR THE PRODUCTION OF A HERBICIDALLY ACTIVE PYRAZOLE COMPOUND | NIPPON SODA CO., LTD. (JP) | 1999-09-07 | — | — | US | claimed |
| EP-0891972-A1 | 3-(ISOXAZOL-5-YL)-SUBSTITUTED BENZOIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1999-01-20 | — | — | EP | claimed |