Phosphoric Acid

Phosphoric Acid

SCHEMBL8522709

C=CC.O=C(O)O.O=P(O)(O)O

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FGFR4 known ✓ P22455 1/20 0.30
LMNA P02545 2/20 0.39
ALDH1A1 P00352 3/20 0.37
CA2 P00918 2/20 0.35
TSHR P16473 4/20 0.33
ALOX15 P16050 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
PEPD P12955 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28334070 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL28405846 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL28992572 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL1075962 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL9397372 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL23630620 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL29255680 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL3818781 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15
Phosphoric Acid SCHEMBL1574062 0.89
Phosphoric Acid SCHEMBL4553439 0.89 CA2 (0.43) LMNAALDH1A1CA2TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2731606-A1 GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE Allergan, Inc. (US) 2014-05-21 EP disclosed
US-20130079379-A1 GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE ALLERGAN, INC. (US) 2013-03-28 US disclosed
WO-2013010032-A1 GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE ALLERGAN, INC. (US) 2013-01-17 WO disclosed
CN-1154133-C Electrolytic solution for capacitor and capacitor ������ѧ��ʽ���� 2004-06-16 CN disclosed
EP-0902446-A2 Electrolytic solution for capacitor and capacitor Mitsui Chemicals, Inc. (JP) 1999-03-17 EP disclosed
CN-1211054-A Electrolytic solution for capacitor and capacitor MITSUI CHEMICALS INC (JP) 1999-03-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130079379-A1 GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE CUTA, PDE3A, PTGIS FGFR4 4192/4885LMNA 2853/4885ALDH1A1 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.