Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229724 | 0.74 | EPHX1 (0.43) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL18528703 | 0.73 | ALDH1A1 (0.38) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL37759 | 0.73 | ALDH1A1 (0.38) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL819854 | 0.72 | MMP2 (0.38) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL18528648 | 0.72 | ALDH1A1 (0.37) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL5099372 | 0.71 | MMP2 (0.44) | MMP2EPHX1 | |
| SCHEMBL6055003 | 0.70 | MMP2 (0.35) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL339626 | 0.69 | SIGMAR1 (0.36) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA | |
| SCHEMBL8623811 | 0.68 | SIGMAR1 (0.46) | SIGMAR1MAOAEPHX1 | |
| SCHEMBL9356142 | 0.68 | MMP2 (0.36) | ALDH1A1SIGMAR1TAAR1SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | claimed |
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | disclosed |