Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819854 | 0.86 | MMP2 (0.38) | MMP2ALDH1A1EPHX1SCN4ASIGMAR1 | |
| SCHEMBL37759 | 0.79 | ALDH1A1 (0.38) | MMP2ALDH1A1EPHX1SIGMAR1SLC6A2 | |
| SCHEMBL339626 | 0.77 | SIGMAR1 (0.36) | MMP2ALDH1A1SIGMAR1SLC6A2TAAR1 | |
| SCHEMBL366500 | 0.73 | CHRNB2 (0.35) | MMP2SIGMAR1 | |
| SCHEMBL11229724 | 0.71 | EPHX1 (0.43) | MMP2EPHX1SIGMAR1SLC6A2TAAR1 | |
| SCHEMBL447452 | 0.69 | ALDH1A1 (0.40) | MMP2ALDH1A1SIGMAR1SLC6A2TAAR1 | |
| SCHEMBL367238 | 0.69 | CHRNB2 (0.38) | MMP2SIGMAR1 | |
| SCHEMBL5099372 | 0.68 | MMP2 (0.44) | MMP2EPHX1 | |
| SCHEMBL18528703 | 0.68 | ALDH1A1 (0.38) | MMP2ALDH1A1EPHX1SIGMAR1SLC6A2 | |
| SCHEMBL8523012 | 0.68 | ALDH1A1 (0.38) | MMP2ALDH1A1EPHX1SIGMAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254556-B1 | Semipermeable thin-film membranes comprising siloxane, alkoxysilyl and aryloxysilyl oligomers and copolymers | BEND RES INC (US) | 1994-11-17 | — | — | EP | disclosed |
| US-4781733-A | GAS SEPARATION, POLYCONDENSATION OF POLYFUNCTIONAL COMPOUNDS | BEND RESEARCH, INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0254556-A2 | Semipermeable thin-film membranes comprising siloxane, alkoxysilyl and aryloxysilyl oligomers and copolymers | BEND RESEARCH, INC. (US) | 1988-01-27 | — | — | EP | disclosed |