SCHEMBL339626

SCHEMBL339626

CCO[Si](OCC)(OCC)C(CNCCN)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.36
ANPEP P15144 1/20 0.34
ERAP2 Q6P179 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
SLC6A2 P23975 2/20 0.34
TAAR1 Q96RJ0 2/20 0.34
MAOA P21397 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MMP2 P08253 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37759 0.86 ALDH1A1 (0.38) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL614548 0.81 ALDH1A1 (0.43) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL339627 0.79 SIGMAR1 (0.42) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL819854 0.79 MMP2 (0.38) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL367238 0.77 CHRNB2 (0.38) SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL9356142 0.77 MMP2 (0.36) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL366500 0.76 CHRNB2 (0.35) SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL2520766 0.74 ANPEP (0.43) SIGMAR1ANPEPSLC6A2TAAR1MAOA
SCHEMBL2526801 0.74 TAAR1 (0.37) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL27791298 0.74 TAAR1 (0.37) SIGMAR1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-11-09 US claimed
WO-2022067351-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2022-03-31 WO claimed
EP-2576472-B1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2016-03-23 EP claimed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US claimed
US-8343624-B2 Durable antireflective film 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-01 US claimed
US-20120135210-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2012-05-31 US claimed
WO-2012018290-A1 DISCRETE COATED NANOPARTICLES KEMPE MARIA (SE) 2012-02-09 WO claimed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
EP-2033020-A2 DURABLE ANTIREFLECTIVE FILM WITH SURFACE MODIFIED INORGANIC NANOPARTICLES 3M Innovative Properties Company (US) 2009-03-11 EP claimed
JP-4166581-B2 2008-10-15 JP claimed
US-20050208308-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-09-22 US claimed
JP-2004536722-A 2004-12-09 JP claimed
US-20040197568-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2004-10-07 US claimed
EP-1401927-A2 FLOUROPOLYMER BONDING 3M Innovative Properties Company (US) 2004-03-31 EP claimed
US-20020197481-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2002-12-26 US claimed
WO-2002094911-A2 FLOUROPOLYMER BONDING 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO claimed
EP-0972303-A1 LOW DIELECTRIC CONSTANT MATERIAL WITH IMPROVED DIELECTRIC STRENGTH W.L. GORE & ASSOCIATES, INC. (US) 2000-01-19 EP claimed
WO-1998044545-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed
WO-1998044546-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed
WO-1998044544-A1 LOW DIELECTRIC CONSTANT MATERIAL WITH IMPROVED DIELECTRIC STRENGTH W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN SIGMAR1 673/4885ANPEP 175/4885ERAP2 3637/4885
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME CAPG, CD47, LMNB1 SIGMAR1 2576/4885ANPEP 2832/4885ERAP2 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.