Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964087 | 0.93 | MAOA (0.47) | SIGMAR1MAOAHTR2AL3MBTL1 | |
| SCHEMBL27812033 | 0.88 | SIGMAR1 (0.44) | SIGMAR1MAOAKDM4ELMNAHTR2A | |
| SCHEMBL9716603 | 0.78 | TDP1 (0.46) | KDM4ELMNAHTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL17417253 | 0.77 | SIGMAR1 (0.39) | SIGMAR1MAOAKDM4ELMNAHTR2A | |
| SCHEMBL37761 | 0.75 | SIGMAR1 (0.42) | SIGMAR1KDM4ELMNA | |
| SCHEMBL15453596 | 0.74 | SIGMAR1 (0.41) | SIGMAR1KDM4ELMNA | |
| SCHEMBL447454 | 0.74 | DRD2 (0.46) | SIGMAR1KDM4ELMNA | |
| SCHEMBL2904115 | 0.74 | TAAR1 (0.50) | SIGMAR1HTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL28175344 | 0.73 | SIGMAR1 (0.44) | SIGMAR1 | |
| Aniline SCHEMBL28077933 | 0.73 | SIGMAR1 (0.38) | SIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | claimed |
| WO-1999063003-A1 | LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 1999-12-09 | — | — | WO | disclosed |