Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523847 | 0.84 | SRD5A1 (0.36) | MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8523105 | 0.84 | SHBG (0.36) | MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8522986 | 0.82 | SRD5A1 (0.35) | MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8639064 | 0.81 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8637608 | 0.79 | TRPC6 (0.34) | MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8524211 | 0.77 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8523652 | 0.76 | SRD5A1 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL8633124 | 0.76 | SRD5A1 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL8637459 | 0.75 | ALDH1A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL9005677 | 0.75 | SRD5A1 (0.56) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |