Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 7/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523844 | 0.86 | CYP19A1 (0.33) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8637459 | 0.83 | ALDH1A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL8633124 | 0.82 | SRD5A1 (0.33) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8523847 | 0.80 | SRD5A1 (0.36) | SRD5A1SRD5A2CYP19A1 | |
| SCHEMBL8523105 | 0.79 | SHBG (0.36) | SRD5A1SRD5A2 | |
| SCHEMBL8522986 | 0.78 | SRD5A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL8523422 | 0.77 | MBOAT4 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8639064 | 0.77 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8642307 | 0.75 | SRD5A1 (0.32) | SRD5A1SRD5A2 | |
| SCHEMBL8996754 | 0.75 | SRD5A1 (0.31) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1998009632-A1 | METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR | MERCK & CO., INC. (US) | 1998-03-12 | — | — | WO | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1998009632-A1 | METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR | MERCK & CO., INC. (US) | 1998-03-12 | — | — | WO | disclosed |