Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 6/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 4/20 | 0.32 |
| ▸ | HRH1 | P35367 | 4/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642307 | 0.89 | SRD5A1 (0.32) | SRD5A1SRD5A2 | |
| SCHEMBL8996754 | 0.89 | SRD5A1 (0.31) | SRD5A1SRD5A2 | |
| SCHEMBL8633124 | 0.88 | SRD5A1 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL8636806 | 0.86 | GPR119 (0.33) | GPR119 | |
| SCHEMBL8639398 | 0.86 | MMP12 (0.30) | — | |
| SCHEMBL8632775 | 0.85 | — | — | |
| SCHEMBL8523650 | 0.85 | — | — | |
| SCHEMBL8677090 | 0.82 | CHRNB2 (0.32) | SRD5A1SRD5A2 | |
| SCHEMBL8522986 | 0.81 | SRD5A1 (0.35) | MBOAT4SRD5A1SRD5A2 | |
| SCHEMBL8679405 | 0.81 | OPRM1 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792371-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0792371-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996012817-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |