Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2115010 | 0.80 | CYP11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4094393 | 0.77 | MAOA (0.33) | — | |
| SCHEMBL2320957 | 0.75 | GAA (0.32) | RARARARBRARG | |
| SCHEMBL4094394 | 0.75 | MGLL (0.33) | — | |
| Hydrochloric Acid SCHEMBL7211600 | 0.74 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL812357 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4059545 | 0.74 | MAOA (0.33) | — | |
| Hydrochloric Acid SCHEMBL4092756 | 0.74 | MAOA (0.33) | — | |
| SCHEMBL29049893 | 0.73 | MAOA (0.35) | — | |
| Hydrochloric Acid SCHEMBL18112870 | 0.73 | ESR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796838-B2 | Polyolefin adhesive compositions and methods of preparing the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20160115306-A1 | Polyolefin Adhesive Compositions and Methods of Preparing the Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-04-28 | — | — | US | disclosed |
| US-5990242-A | Propylene/ethylene-α-olefin block copolymer and process for processing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |