SCHEMBL8523698

SCHEMBL8523698

CCCCCN1CNc2cc(Cl)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
GRIA2 P42262 1/20 0.37
CNR2 P34972 2/20 0.37
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36
PSENEN Q9NZ42 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRA6 Q16445 1/20 0.35
CYP1A1 P04798 2/20 0.35
CRHR1 P34998 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9038436 0.82 HDAC1 (0.39) HDAC1GAA
SCHEMBL9041570 0.82 HDAC1 (0.39) HDAC1GAA
SCHEMBL8524212 0.82 SIGMAR1 (0.38) HDAC1KDM4EGAACYP1A1LMNA
SCHEMBL8523710 0.80 SCN9A (0.39) HDAC1KDM4ECYP1A1
SCHEMBL8523151 0.79 DRD2 (0.40) HDAC1KDM4E
SCHEMBL9038711 0.77 CES1 (0.44) KDM4ECNR2LMNA
SCHEMBL9482548 0.75 KDM4E (0.42) KDM4EGAACNR2PSEN1PSEN2
SCHEMBL11206551 0.72 CRHR1 (0.49) HDAC1KDM4EGAACRHR1
SCHEMBL19936573 0.69 HDAC1 (0.40) HDAC1KDM4EGAALMNA
SCHEMBL24731338 0.67 KMT2A (0.36) KDM4EGRIA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed