Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854100 | 0.74 | MEN1 (0.44) | NISCHMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7034013 | 0.69 | TNF (0.43) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL8523698 | 0.69 | HDAC1 (0.39) | HDAC1GAAKDM4ELMNA | |
| SCHEMBL9038436 | 0.69 | HDAC1 (0.39) | HDAC1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL8523710 | 0.67 | SCN9A (0.39) | HDAC1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19705148 | 0.66 | HDAC1 (0.56) | HDAC1MEN1KMT2AGAAKDM4E | |
| SCHEMBL8091908 | 0.65 | BRPF1 (0.41) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL22278561 | 0.64 | ADORA3 (0.36) | NISCHMEN1KMT2AGAAKDM4E | |
| SCHEMBL20888870 | 0.62 | HTR3E (0.39) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9038711 | 0.62 | CES1 (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594555-B1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA PHARM CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |