SCHEMBL8523710

SCHEMBL8523710

CCCCCN1CNc2cc(OC)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.39
CYP1A1 P04798 1/20 0.38
HDAC1 Q13547 1/20 0.38
DYRK1A Q13627 1/20 0.38
TLR8 Q9NR97 3/20 0.36
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PLA2G2A P14555 1/20 0.35
FSHR P23945 1/20 0.35
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35
HTR3D Q70Z44 1/20 0.35
HTR3C Q8WXA8 1/20 0.35
HTR1A P08908 1/20 0.35
GHSR Q92847 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20888870 0.84 HTR3E (0.39) DYRK1AALDH1A1HTR3EHTR3BHTR3A
SCHEMBL9038436 0.80 HDAC1 (0.39) HDAC1TLR8NPC1ALDH1A1CYP1A2
SCHEMBL9041570 0.80 HDAC1 (0.39) HDAC1TLR8NPC1ALDH1A1CYP1A2
SCHEMBL8523698 0.80 HDAC1 (0.39) CYP1A1HDAC1KDM4E
SCHEMBL8524767 0.77 HRH3 (0.40) NPC1ALDH1A1HTR3EHTR3BHTR3A
SCHEMBL8523151 0.77 DRD2 (0.40) HDAC1ALDH1A1KDM4E
SCHEMBL9482943 0.77 MEN1 (0.39) SCN9ACYP1A1DYRK1ATLR8ALDH1A1
SCHEMBL9038711 0.75 CES1 (0.44) ALDH1A1HTR1AKDM4ECYP1A2CYP2D6
SCHEMBL8524212 0.74 SIGMAR1 (0.38) CYP1A1HDAC1KDM4EMEN1KMT2A
SCHEMBL8091908 0.71 BRPF1 (0.41) NPC1ALDH1A1KDM4ECYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed