Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 12/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523935 | 0.82 | NPC1 (0.44) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8525368 | 0.76 | SMN1; SMN2 (0.60) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8523986 | 0.75 | CDK5 (0.40) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8525110 | 0.74 | CDK5 (0.42) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8525270 | 0.71 | SMN1; SMN2 (0.70) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8524484 | 0.69 | KDM4E (0.40) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8484612 | 0.69 | RAB9A (0.47) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8524764 | 0.69 | CYP19A1 (0.45) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5902599 | 0.69 | CDK5 (0.60) | CDK5CDK5R1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16132462 | 0.68 | MAPT (0.46) | RAB9ANPC1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |