Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642307 | 0.91 | SRD5A1 (0.32) | SRD5A1SRD5A2 | |
| SCHEMBL8633124 | 0.91 | SRD5A1 (0.33) | SRD5A1SRD5A2 | |
| SCHEMBL8637608 | 0.89 | TRPC6 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8639398 | 0.89 | MMP12 (0.30) | — | |
| SCHEMBL8636806 | 0.89 | GPR119 (0.33) | — | |
| SCHEMBL8632775 | 0.88 | — | — | |
| SCHEMBL8523650 | 0.88 | — | — | |
| SCHEMBL8677090 | 0.84 | CHRNB2 (0.32) | SRD5A1SRD5A2 | |
| SCHEMBL8522986 | 0.83 | SRD5A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL8679405 | 0.83 | OPRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724592-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO. INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011254-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | disclosed |