Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475608 | 0.81 | KMT2A (0.51) | HCRTR1HCRTR2MGLLALDH1A1POLB | |
| SCHEMBL8490615 | 0.81 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL8189685 | 0.80 | ALDH1A1 (0.47) | HCRTR1MGLLALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8490965 | 0.76 | F9 (0.42) | ALDH1A1SMYD3 | |
| SCHEMBL1822912 | 0.76 | KDM4E (0.36) | HCRTR1HCRTR2POLBKMT2ASMYD3 | |
| SCHEMBL299870 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2MGLLALDH1A1POLB | |
| SCHEMBL30982330 | 0.74 | HCRTR1 (0.51) | HCRTR1HCRTR2MGLLALDH1A1POLB | |
| SCHEMBL403908 | 0.74 | HCRTR1 (0.51) | HCRTR1HCRTR2MGLLALDH1A1POLB | |
| SCHEMBL8525971 | 0.73 | PCSK9 (0.38) | ALDH1A1KMT2ASMYD3MEN1 | |
| SCHEMBL8524846 | 0.73 | CTSS (0.40) | ALDH1A1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |