Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526227 | 0.87 | NR4A2 (0.32) | NR4A2 | |
| SCHEMBL8501778 | 0.85 | NR4A2 (0.34) | NR4A2RIPK1CYP2C19HIF1ARBP4 | |
| SCHEMBL6843332 | 0.81 | NR4A2 (0.33) | NR4A2CYP2C19HIF1A | |
| SCHEMBL8663987 | 0.81 | NR4A2 (0.33) | NR4A2CYP2C19HIF1A | |
| SCHEMBL8525557 | 0.81 | DHFR (0.31) | NR4A2 | |
| SCHEMBL8499414 | 0.72 | MAPT (0.32) | NR4A2CYP2C19HIF1A | |
| SCHEMBL8501573 | 0.72 | NR4A2 (0.37) | NR4A2CYP2C19HIF1A | |
| SCHEMBL8501943 | 0.70 | CYP1A2 (0.32) | CYP2C19 | |
| SCHEMBL5014696 | 0.70 | POLB (0.33) | RIPK1CYP2C19 | |
| SCHEMBL11761413 | 0.69 | NR4A2 (0.37) | NR4A2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927156-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009940-A1 | BIPHENYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |